Contact Info

Biography

Website: https://rowanbmegalie.com/

Education:
Post-Doctoral, University of Pennsylvania, Institute for Medicine & Engineering
Ph.D., Biomedical Engineering, University of Michigan
M.S., Biomedical Engineering, Rensselaer Polytechnic Institute
B.S., Mechanical & Aerospace Engineering, Princeton

Impactful Research Areas:
Health
    Biomedical
Sustainability
    Sustainable Materials & Processes

Research Expertise:
Mechanobiology; Tissue Engineering; Blood-Brain Barrier

Recent Publications:
CD44 mediates shear stress mechanotransduction in an in vitro blood‐brain barrier model through small GTPases RhoA and Rac1
BJ DeOre, PP Partyka, F Fan, PA Galie
The FASEB Journal 36 (5), e22278, 2022

Microindentation of Fluid-Filled Cellular Domes Reveals the Contribution of RhoA-ROCK Signaling to Multicellular Mechanics
BJ DeOre, A Baldwin-LeClair, KA Tran, A DaSilva, FJ Byfield, PA Janmey, ...
Small, e2200883, 2022

Magnetic alignment of injectable hydrogel scaffolds for spinal cord injury repair
KA Tran, Y Jin, J Bouyer, BJ DeOre, Ł Suprewicz, A Figel, H Walens, ...
Biomaterials Science 10 (9), 2237-2247, 2022

SARS-CoV-2 Spike Protein Disrupts Blood–Brain Barrier Integrity via RhoA Activation
BJ DeOre, KA Tran, AM Andrews, SH Ramirez, PA Galie
Journal of Neuroimmune Pharmacology, 1-7, 2021

Implementation and characterization of a physiologically relevant flow waveform in a 3D microfluidic model of the blood–brain barrier
N Bouhrira, BJ DeOre, PA Galie
Biotechnology and Bioengineering 118 (7), 2411-2421, 2021